Taipei Medical University Institutional Repository:Item 987654321/6353
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 45422/58598 (78%)
造访人次 : 2533506      在线人数 : 257
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://libir.tmu.edu.tw/handle/987654321/6353


    题名: Structure-solubility relationships among inclusion complexation of hydroxypropyl--cyclodextrin with bicyclic drugs
    作者: 胡健民
    Hu, Jian-Min
    贡献者: 藥學研究所
    关键词: 包覆錯合
    氫氧丙基--環糊精
    5
    8-二氫氧基-1
    4-酮類衍生物(6+6環)
    類衍生物(6+5環)
    對位-氫氧基苯甲酸酯纇衍生物
    藥物學
    complexation
    5
    8-dihydroxy-1
    4-naphthoquinone derivatives (6+6 ring structure)
    indole derivatives (6+5 ring structure)
    p-hydroxybenzoic acid esters
    PHARMACOLOGY
    日期: 1986
    上传时间: 2009-09-11 16:52:32 (UTC+8)
    摘要: The complexation of hydroxypropyl--cyclodextrin with bicyclic
    compounds was studied. 5,8-Dihydroxy-1,4-naphthoquinone
    derivatives(6+6 ring structure) and indole derivatives (6+5 ring
    structure) were used as the model chemicals and the solubility
    increment was employed as an indicator to monitor the
    complexation progress. The solubility experiments revealed that
    the position and 3-dimensional structure of the substituents
    provided more impact on the solubility increment than the
    polarity and chain length did. This result indicated that both
    the position and 3-dimensional structure were the major
    determinants affecting the complexation among the factors
    studied. The control study with monocyclic compounds, using p-
    hydroxybenzoic acid esters as the model chemicals, showed
    opposite results. These results suggested that complexation of
    hydroxypropyl--cyclodextrin with monocyclic compounds had a
    different complexation mechanism with the bicyclic compounds.
    数据类型: thesis
    显示于类别:[藥學系] 博碩士論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    摘要.doc25KbMicrosoft Word84检视/开启
    摘要.pdf1189KbAdobe PDF96检视/开启
    摘要.ppt95KbMicrosoft Powerpoint154检视/开启
    摘要.ps147KbPostscript65检视/开启


    在TMUIR中所有的数据项都受到原著作权保护.

    TAIR相关文章

    著作權聲明 Copyright Notice

    • 本平台之數位內容為臺北醫學大學所收錄之機構典藏，包含體系內各式學術著作及學術產出。秉持開放取用的精神，提供使用者進行資料檢索、下載與取用，惟仍請適度、合理地於合法範圍內使用本平台之內容，以尊重著作權人之權益。商業上之利用，請先取得著作權人之授權。

      The digital content on this platform is part of the Taipei Medical University Institutional Repository, featuring various academic works and outputs from the institution. It offers free access to academic research and public education for non-commercial use. Please use the content appropriately and within legal boundaries to respect copyright owners' rights. For commercial use, please obtain prior authorization from the copyright owner.

    • 瀏覽或使用本平台，視同使用者已完全接受並瞭解聲明中所有規範、中華民國相關法規、一切國際網路規定及使用慣例，並不得為任何不法目的使用TMUIR。

      By utilising the platform, users are deemed to have fully accepted and understood all the regulations set out in the statement, relevant laws of the Republic of China, all international internet regulations, and usage conventions. Furthermore, users must not use TMUIR for any illegal purposes.

    • 本平台盡力防止侵害著作權人之權益。若發現本平台之數位內容有侵害著作權人權益情事者，煩請權利人通知本平台維護人員([email protected])，將立即採取移除該數位著作等補救措施。

      TMUIR is made to protect the interests of copyright owners. If you believe that any material on the website infringes copyright, please contact our staff([email protected]). We will remove the work from the repository.

    Back to Top
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈