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    Taipei Medical University Institutional Repository > 生藥學研究所 >  資料類型相關文件 社群詳細資訊

    簡介：台北醫學大學有關生藥之研究，起始於民國五十二年（一九六三年），台北醫學院首任院長故徐千田博士遠赴日本國立京都大學禮聘顏焜熒教授返國，建立首座植物化學研究室，除負責本學院生藥學及中藥相關化學課程之教學外，亦是本學校研究生藥之骨幹。於民國七十二年，本校第一所研究所－藥學研究所成立時，招收首屆生藥組碩士班學生，並於民國七十五年成立博士班。七十九年十二月胡俊弘院長為配合健康科學大學之設立，擴大藥學院之架構，向教育部提出「生藥學研究所」之申請，隔年十一月十八日奉教育部台 (80) 高 61500字號函核准，並經院務會議通過，成立台灣第一所「生藥學研究所」，由顏焜熒教授擔任首任所長。第一屆碩士班研究生於八十一年六月正式招生，而於八十三年六月有第一屆畢業生，同年八月由楊玲玲教授接任第二任所長，直至八十九年七月屆滿。其後行政業務由李美賢副教授及徐鳯麟教授暫代，九十年八月續由徐鳯麟教授正式接掌本所，積極新聘兼任教師，規劃教學、研究及課程之整合。並於李美賢副教授、王靜瓊副教授、侯文琪副教授、陳彥州副教授、梁文俐助理教授之外，陸續增聘李慶國教授、李宗徽助理教授、盧重光助理教授、楊文彬助理教授、蔡祐輔助理教授等，增加教學陣容。自成立至九十五學年度為止，已孕育了十四屆畢業生。

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    類別 日期 題名 作者 檔案
    [生藥學研究所] 期刊論文 2015 Glycine hydroxamate inhibits tyrosinase activity and melanin contents through downregulating cAMP/PKA signaling pathways YS, Lin; WC, Wu; SY, Lin; WC, Hou
    [生藥學研究所] 期刊論文 2015 Effects of yam dioscorin interventions on improvements of the metabolic syndrome in high-fat diet-induced obese rats SL, Shih; YS, lin; SY, Lin; WC, Hou
    [生藥學研究所] 期刊論文 2015 Neurocytoprotective Effects of Aliphatic Hydroxamates from Lovastatin, a Secondary Metabolite from Monascus-Fermented Red Mold Rice, in 6-Hydroxydopamine (6-OHDA)-Treated Nerve Growth Factor (NGF)-Differentiated PC12 Cells CM, Lin; TY, Lin; RD, Lin; WJ, Huang; MH, Lee
    [生藥學研究所] 期刊論文 2014 Development of an Anti-Methoxy Poly(ethylene glycol) (α-mPEG) Cell-Based Capture System to Measure mPEG and mPEGylated Molecules Chuang, Kuo-Hsiang; Kao, Chien-Han; Roffler, Steve R.; Lu, Ssu-Jung; Cheng, Ta-Chun; Wang, Yun-Ming; Chuang, Chih-Hung; Hsieh, Yuan-Chin; Wang, Yeng-Tseng; Weng, Kuo-Yi; Cheng, Tian-Lu
    [生藥學研究所] 期刊論文 2014 Discovery of specific inhibitors for intestinal E coli. ?-glucuronidase through in silico virtual screening Cheng, Ta-Chun; Chuang, Kuo-Hsiang; Roffler, Steve; Cheng, Kai-Wen; Leu, Yu-Lin; Chuang, Chih-Hung; Huang, Chien-Chaio; Kao, Chien-Han; Hsieh, Yuan-Chin; Cheng, Tian-Lu; Chen, Chien-Shu
    [生藥學研究所] 期刊論文 2014 A histone deacetylase inhibitor YCW1 with antitumor and antimetastasis properties enhances cisplatin activity against non-small cell lung cancer in preclinical studies WJ, Huang; YA, Tang; MY, Chen; YJ, Wang; FH, Hu; TW, Wang; SW, Chao; HW, Chiu; YL, Yeh; HY, Chang; HF, Juan; Lin, P; YC, Wang
    [生藥學研究所] 期刊論文 2014 High-Throughput Sorting of the Highest Producing Cell via a Transiently Protein-Anchored System KH, Chuang; YC, Hsieh; IS, Chiang; CH, Chuang; CH, Kao; TC, Cheng; YT, Wang; WW, Lin; BM, Chen; SR, Roffler; MY, Huang; TL, Cheng
    [生藥學研究所] 期刊論文 2014 A Novel Hydroxysuberamide Derivative Potentiates MG132-Mediated Anticancer Activity Against Human Hormone Refractory Prostate Cancers TheRoleof Histone Deacetylase and Endoplasmic Reticulum Stress YC, Chen; WJ, Huang; JL, Hsu; CC, Yu; WT, Wang; JH, Guh
    [生藥學研究所] 期刊論文 2014 Acacetin inhibits glutamate release and prevents kainic acid-induced neurotoxicity in rats TY, Lin; WJ, Huang; CC, Wu; CW, Lu; SJ, Wang
    [生藥學研究所] 期刊論文 2014 N-Hydroxycinnamide derivatives of osthole inhibit cell migration and invasion by suppressing Smad2 and Akt pathways in human colorectal adenocarcinoma cells LY, Liu; WJ, Huang; FM, Ho; RJ, Lin; SY, Lin; FM, Suk; YC, Liang
    [生藥學研究所] 期刊論文 2014 A Taiwanese Propolis Derivative Induces Apoptosis through Inducing Endoplasmic Reticular Stress and Activating Transcription Factor-3 in Human Hepatoma Cells FM, Suk; GS, Lien; WJ, Huang; CN, Chen; SY, Lu; YC, Yang; MD, Yan; YC, Liang
    [生藥學研究所] 期刊論文 2014 One-step mixing with humanized anti-mPEG bispecific antibody enhances tumor accumulation and therapeutic efficacy of mPEGylated nanoparticles CH, Kao; JY, Wang; KH, Chuang; CH, Chuang; TC, Cheng; YC, Hsieh; YL, Tseng; BM, Chen; SR, Roffler; TL, Cheng
    [生藥學研究所] 期刊論文 2014 Studies on anti-inflammatory activity of sulfated polysaccharides from cultivated fungi Antrodia cinnamomea JJ, Cheng; CH, Chao; PC, Chang; MK, Lu
    [生藥學研究所] 期刊論文 2014 Stimulation of osteogenic activity in human osteoblast cells by edible Uraria crinita Mao, Yi-Wen; Lin, Rong-Dih; Hung, Hsiao-Chiao; Lee, Mei-Hsien
    [生藥學研究所] 期刊論文 2014 DNMT3B Overexpression by Deregulation of FOXO3a-Mediated Transcription Repression and MDM2 Overexpression in Lung Cancer Yang, Yi-Chieh; Tang, Yen-An; Shieh, Jiunn-Min; Lin, Ruo-Kai; Hsu, Han-Shui; Wang, Yi-Ching
    [生藥學研究所] 期刊論文 2014 Antioxidant and antiglycation activities of the synthesised dipeptide, Asn-Trp, derived from computer-aided simulation of yam dioscorin hydrolysis and its analogue, Gln-Trp CH, Han; YS, Lin; SY, Lin; WC, Hou
    [生藥學研究所] 期刊論文 2014 Mimicking the germinal center reaction in hybridoma cells to isolate temperature-selective anti-PEG antibodies YC, Su; TS, Al-Qaisi; HY, Tung; TL, Cheng; KH, Chuang; BM, Chen; SR, Roffler
    [生藥學研究所] 期刊論文 2014 Vasorelaxing and antihypertensive activities of synthesized peptides derived from computer-aided simulation of pepsin hydrolysis of yam dioscorin YS, Lin; YL, Lu; GJ, Wang; HJ, Liang; WC, Hou
    [生藥學研究所] 期刊論文 2014 Asn-Trp dipeptides improve the oxidative stress and learning dysfunctions in D-galactose-induced BALB/c mice CH, Han; YS, Lin; TL, Lee; HJ, Liang; WC, Hou
    [生藥學研究所] 期刊論文 2014 Evaluation of the antihyperuricemic activity of phytochemicals from Davallia formosana by enzyme Assay and hyperuricemic mice model CY, Chen; CC, Huang; KC, Tsai; WJ, Huang; WC, Huang; YC, Hsu; FL, Hsu
    [生藥學研究所] 期刊論文 2014 Cucurbitane-type glycosides from the fruits of Momordica charantia and their hypoglycaemic and cytotoxic activities LJ, Zhang; CC, Liaw; PC, Hsiao; HC, Huang; MJ, Lin; ZH, Lin; FL, Hsu; YH, Kuoa
    [生藥學研究所] 期刊論文 2014 Effects of yam tuber protein, dioscorin, on attenuating oxidative status and learning dysfunction in D-galactose-induced BALB/c mice CH, Han; YF, Lin; YS, Lin; TL, Lee; WJ, Huang; SY, Lin; WC, Hou
    [生藥學研究所] 期刊論文 2014 Diterpene glycosides and polyketides from Xylotumulus gibbisporus YC, Chang; CK, Lu; YR, Chiang; GJ, Wang; YM, Ju; YH, Kuo; TH, Lee
    [生藥學研究所] 期刊論文 2014 Aliphatic phenolic ethers from Trichobotrys effusa JJ, Chen; SW, Wang; HY, Hsiao; MS, Lee; YH, Kuo; TH, Lee
    [生藥學研究所] 期刊論文 2014 Cephalochromin from Cosmospora vilior Induces G0/G1 Cell Cycle Arrest and Apoptosis in A549 Human Non-Small Cell Lung Cancer Cells by Inflicting Mitochondrial Disruption CJ, Hsiao; Hsiao, G; WL, Chen; SW, Wang; CP, Chiang; LY, Liu; JH, Guh; TH, Lee; CL, Chung
    [生藥學研究所] 期刊論文 2014 Antroquinonol D, isolated from Antrodia camphorate, with DNA demethylation and anti-cancer potential Wang, Sheng-Chao; Lee, Tzong-Huei; Hsu, Chun-Hua; Chang, Yu-Jia; Chang, Man-Shan; Wang, Yi-Ching; Ho, Yuan-Soon; Wen, Wu-Che; Lin, Ruo-Kai
    [生藥學研究所] 期刊論文 2014 A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase I CC, Yu; SL, Pan; SW, Chao; SP, Liu; JL, Hsu; YC, Yang; TK, Li; WJ, Huang; JH, Guh
    [生藥學研究所] 期刊論文 2014 Dysregulated transcriptional and post-translational control of DNA methyltrasferases in cancer Lin, Ruo-Kai; Wang, Yi-Ching
    [生藥學研究所] 期刊論文 2008 A Dose-Dependent Pharmacokinetic Study of Levodopa by Intramuscular Administration in Rabbits 徐鳳麟; Wang LH; Hsu KY; Hsu FL; Lin SJ
    [生藥學研究所] 期刊論文 2007 A high-resistance-starch rice diet reduces glycosylated hemoglobin levels and improves the antioxidant status in diabetic rats 侯文琪; Shih CK; Chen SH; Hou WC; Cheng HH
    [生藥學研究所] 期刊論文 2007 A New Cytotoxic Agent from Solid-State Fermented Mycelium of Antrodia camphorata 李宗徽; Tzong-Huei Lee; Ching-Kuo Lee; Wan-Lin Tsou; Sheng-Yung Liu; Mao-Tien Kuo; Wu-Che Wen
    [生藥學研究所] 期刊論文 2008 A New Sulfonamide Compound as an Orally Active Dipeptidyl Peptidase IV Inhibitor – Structure and Activity Relationship of Arylsulfonamide to Dipeptidyl Peptidase IV Inhibition 徐鳳麟; Tsai HJ; Chou SY; Chuang SH; Chen CC; Hsu FL
    [生藥學研究所] 期刊論文 2007 Ancordin, the major rhizome protein of madeira-vine, with trypsin inhibitory and stimulatory activities in nitric oxide productions 侯文琪; Chuang MT; Lin YS; Hou WC
    [生藥學研究所] 期刊論文 2007 Anemonin is a natural bioactive compound that can regulate tyrosinase-related proteins and mRNA in human melanocytes 徐鳳麟; 李美賢; 李宗徽; Huang YH; Lee TH; Chan KJ; Hsu FL; Wu YC; Lee MH
    [生藥學研究所] 期刊論文 2008 Anemonin, from Clematis crassifolia, potent and selective inducible 李宗徽; Lee TH; Huang NK; Lai TC; Yang ATY; Wang GJ
    [生藥學研究所] 期刊論文 2007 Antihypertensive activities of a solid-state culture of Taiwanofungus camphoratus (Chang-Chih) in spontaneously hypertensive rats 侯文琪; Liu DZ; Liang YC; Lin SY; Lin YS; Wu WC; [Hou WC; Su CH]
    [生藥學研究所] 期刊論文 2008 Antioxidant and nitric oxide production inhibitory activities of galacturonyl hydroxamic acid 侯文琪; Liu YH; Lin SY; Lee CC; Hou WC
    [生藥學研究所] 期刊論文 2007 Antioxidant and semicarbazide-sensitive amine oxidase inhibitory activities of alginic acid hydroxamates 侯文琪; Liu DZ; Wu WC; Liang HJ; Hou WC
    [生藥學研究所] 期刊論文 2008 Antioxidant, anti-semicarbazide-sensitive amine oxidase, and antihypertensive activities of geraniin isolated from Phyllanthus urinaria 侯文琪; Lin SY; Wang CC; Lu YL; Wu WC; Hou WC
    [生藥學研究所] 期刊論文 2008 Bidenphytins A and B, unexpected novel pheophytin peroxides from the leaves of Biden pilosa Linn. var. radiate Sch. Bip. 李宗徽; Lee TH; Lu CK; Lo JM; Kuo YH; Lee CK
    [生藥學研究所] 期刊論文 2007 Biotransformation of Gallic Acid by Beauveris sulfurescens ATCC 7159 徐鳳麟; Hsu FL; Yang LMChang SF; Wang LH; Hsu CY; Liu PC; Lin SJ
    [生藥學研究所] 期刊論文 2007 Comparative anti-inflammatory characterization of wild fruiting body, liquid-state fermentation, and solid-state culture of Taiwanofungus camphoratus in microglia and the mechanism of its action 李宗徽; D. Z. Liu; H. J. Li; C. H. Chen; C. H Su; T. H. Lee; W. C. Hou; S. Y. Lin; W. B. Zhong; P. J. Lin; L. F
    [生藥學研究所] 期刊論文 2007 Constituents from the Formosan apple reduce tyrosinase activity in human epidermal melanocytes 李美賢; 徐鳳麟; Lin YP; Hsu FL; Chen CS; Chern JW; Lee MH
    [生藥學研究所] 期刊論文 2007 DPPH radical scavenging, semicarbazide-sensitive amine oxidase inhibitory and cytotoxic activities of Taiwanofungus camphoratus (Chang-Chih) 侯文琪; Wang GJ; Lin SY; Wu WC; Hou WC
    [生藥學研究所] 期刊論文 2009 Effects of different types of yam (Dioscorea alata) products on the blood pressure of spontaneously hypertensive rats. 侯文琪; Liu; Y. H.; Lin; Y. S; Liu; D. Z.; Han; C. H.; Chen; C. T.; Fan; M.; and Hou; W. C.
    [生藥學研究所] 期刊論文 2007 Epigallocatechin gallate, the most active polyphenolic catechin in green tea, presynaptically facilitates Ca2+-dependent glutamate release via activation of protein kinase C in rat cerebral cortex. 黃偉展; Chou CW; Huang WJ; Tien LT; Wang SJ
    [生藥學研究所] 期刊論文 2008 Feeding trial of instant food containing lyophilized yam powder in hypertensive subjects 侯文琪; Liu DZ; Liang HJ; Han CH; Lin SY; Chen CT; Fan M and Hou WC
    [生藥學研究所] 期刊論文 2008 Flavonoids with iNOS inhibitory activity from Pogonatherum crinitum 李宗徽; Wang GJ; Chen YM; Wang TM; Lee CK; Chen KJ; Lee TH
    [生藥學研究所] 期刊論文 2009 Flaxseed protein-derived peptide fractions: Antioxidant properties and inhibition of lipopolysaccharide-induced nitric oxide production in murine macrophages. 侯文琪; Udenigwe; C. C.; Lu; Y. L.; Han; C. H.; Hou; W. C.; Aluko; R. E.
    [生藥學研究所] 期刊論文 2008 Ginsenosides Rg1 and Rb1 enhance glutamate release through activation of protein kinase A in rat cerebrocortical nerve terminals (synaptosomes) 黃偉展; Chang Y; Huang WJ; Tien LT; Wang SJ

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