Laparoscopy-Guided Myometrial Biopsy in the Definite Diagnosis of Diffuse Adenomyosis.

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Taipei Medical University Institutional Repository > 醫學院 > 醫學系 > 婦產學科 > 期刊論文 > Item 987654321/874

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題名:	Laparoscopy-Guided Myometrial Biopsy in the Definite Diagnosis of Diffuse Adenomyosis.
作者:	鄭丞傑 Jeng CJ;Huang SH;Shen J;Chou CS;Tzeng CR
貢獻者:	婦產學科
日期:	2007
上傳時間:	2009-08-13 15:50:37 (UTC+8)
摘要:	BACKGROUND: The purpose of this study was to investigate the usefulness of laparoscopy-guided myometrial biopsy in the diagnosis of diffuse adenomyosis. METHODS: This prospective non-randomized study (Canadian Task Force classification II-1) was conducted in a tertiary medical center. One hundred patients who had clinical signs and symptoms strongly suggestive of adenomyosis were included as the study sample. Transvaginal sonography, serum CA-125 determination and laparoscopy-guided myometrial biopsy were performed. RESULTS: The mean largest myometrial thickness was 3.10+/-0.56 cm (range 2.30-4.50). The mean serum CA-125 level was 49.64+/-38.30 U/ml (range 10.90-205.28). Of these 100 patients, adenomyosis was pathologically proven in 92 patients, small leiomyoma in four patients and myometrial hypertrophy in four patients. The sensitivity of myometrial biopsy was 98% and the specificity 100%; the positive predictive value was 100% and the negative predictive value 80%, which were superior to those of transvaginal sonography, serum CA-125 determination or the combination of both. CONCLUSION: Laparoscopy-guided myometrial biopsy is a valuable tool for obtaining a definite diagnosis of diffuse adenomyosis with preservation of the uterus in infertility workup or in the evaluation of dysmenorrhea or chronic pelvic pain.
關聯:	Human Reprod.22(7):2016-2019.
資料類型:	article
顯示於類別:	[婦產學科] 期刊論文

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