Taipei Medical University Institutional Repository:Item 987654321/65337
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    题名: Red Clover Isoflavones Influence Estradiol Concentration, Exercise Performance, and Gut Microbiota in Female Mice.
    作者: 邱彥碩
    Yi-Ming Chen, I-Lin Wang, Xin-Yi Zhu, Wan-Chun Chiu, Yen-Shuo Chiu
    贡献者: 保健營養學系
    日期: 2021-04
    上传时间: 2025-03-31 11:45:12 (UTC+8)
    摘要: Abstract
    In red clover (Trifolium pratense L.; RC) the main compound is isoflavones, which are selective estrogen receptor modulators for maintaining female health. Isoflavones exert antifatigue effects during exercise in high-temperature environments. This study aimed to investigate the effect of RC supplementation on gut microbiota composition to determine whether it improves intestinal barrier function and exercise performance. Female ICR mice were divided into four groups (n = 8 per group) and orally administered RC once daily for 6 weeks at 0 (vehicle), 308 (RC-1X), 615 (RC-2X), and 1,538 (RC-5X) mg/kg. RC supplementation decreased the fat mass and increased exhaustive swimming time, grip strength, and muscle glycogen in female mice. In the RC supplementation group, serum levels of lactate, ammonia, and creatine kinase decreased after swimming. The estradiol and progesterone levels were higher in the RC group than in the vehicle group. Regarding gut microbiota composition, the RC-2X group may increase intestinal health related to the microorganisms Pseudobutyrivibrio and Parabacteroide. Thus, the use of RC supplements as nutraceuticals could have positive effects on athletes' gut and overall health.
    關聯: Front Nutr. 2021 Apr 14; 8: 623698
    描述: 【111-1 升等】臺北醫學大學教師升等專門著作
    職別：兼任
    送審等級：副教授
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    数据类型: article
    显示于类别:[教師升等送審著作] 111

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