| 摘要: | 背景：早產兒出生後在新生兒加護病房接受治療，面臨如過多的光線與噪音下等有害刺激，影響早產兒生理穩定。積極的感官介入，有可能促進生理與行為的穩定，改善嬰兒感官體驗。因此本研究目的提供母親的聲音刺激作為介入，探討使用保溫箱外裝置播音器播放母親聲音對早產兒生理與行為穩定度的成效。
方法：本研究是採單盲、平行、雙臂隨機分派設計，分派至實驗組(在保溫箱外播放母親聲音為介入)與控制組。母親聲音的介入是錄製母親閱讀三本童書的音檔，連續十四天每天三次在餵奶時間，每次播放30 分鐘母親聲音。以床邊生理監視器收集第0天、第七天以及第十四天每分鐘心跳速率、呼吸速率以及血氧飽和濃度，行為狀態則選擇觀察每日的哭泣行為；介入結果為計算第0天、第七天以及第十四天的生理穩定度(心跳速率、呼吸速率、血氧濃度以及心肺不良事件)，以及第0天、第七天以及第十四天整天的哭泣次數。
結果: 研究於2022年09月至2024年02月期間進行，共收實驗組12位以及控制組13位早產兒。母親聲音介入在早產兒心跳速率穩定度在第七天(p=.42)及第十四天(p=.24)均無顯著；在呼吸速率穩定度在第七天(p=.02)及第十四天(p=.00)均有顯著成效；在血氧濃度穩定度第七天(p=.18)沒有顯著成效，在第十四天(p=.00)有顯著成效；在心肺不良事件第七天(p=.06)，在第十四天(p=.09)均無顯著成效；在哭泣次數第七天(p=.80)，在第十四天(p=.14)亦均無顯著成效。
結論: 這個以媽媽聲音為介入的臨床試驗，對早產兒的呼吸次數與血氧濃度的穩定度有成效，未來將可以應用在新生兒加護病房，有助於早產兒生理及行為的穩定。
Background:
Preterm infants receive treatment in the neonatal intensive care unit after birth, facing harmful stimuli such as excessive light and noise, which affect their physiological stability. Positive sensory interventions may promote physiological and behavioral stability and improve infants' sensory experiences. Therefore, the purpose of this study is to provide maternal voice stimulation as an intervention, exploring the effectiveness of using an external incubator device to play the mother's voice on the physiological and behavioral stability of preterm infants.
Method:
This study adopts a single-blind, parallel, two-arm randomized design, assigning participants to an experimental group (with maternal voice playback outside the incubator as an intervention) and a control group. The maternal voice intervention involves recording audio files of the mother reading three children's books, played three times daily for 30 minutes during feeding time over fourteen consecutive days. Physiological data, including heart rate, respiratory rate, and blood oxygen saturation, are collected using bedside monitors on days 0, 7, and 14, with daily observations of crying behavior to assess behavioral state. The intervention results are evaluated by calculating physiological stability (heart rate, respiratory rate, blood oxygen saturation, and cardiopulmonary adverse events) and the total number of crying episodes throughout the day on days 0, 7, and 14.
Results
The study was conducted from September 2022 to February 2024, involving 12 preterm infants in the experimental group and 13 in the control group. The maternal voice intervention did not show a significant effect on heart rate stability on day 7 (p = .42) and day 14 (p = .24). However, it showed a significant effect on respiratory rate stability on day 7 (p = .02) and day 14 (p = .00). For blood oxygen saturation stability, there was no significant effect on day 7 (p = .18), but there was a significant effect on day 14 (p = .00). There was no significant effect on cardiopulmonary adverse events on day 7 (p = .06) and day 14 (p = .09). Additionally, there was no significant effect on the number of crying episodes on day 7 (p = .80) and day 14 (p = .14).
Conclusion:
This clinical trial using maternal voice as an intervention showed effectiveness in stabilizing the respiratory rate and blood oxygen saturation of preterm infants. In the future, this approach can be applied in neonatal intensive care units to help improve the physiological and behavioral stability of preterm infants. |
