| 摘要: | 研究骨質疏鬆症和骨鬆肌少症患者之營養狀態，與骨質密度、身體 組成及血中鈣與維生素 D 之相關性。
招募對象為 50 歲以上之骨質疏鬆症、肌少症、骨鬆肌少症高風險 患者，分為四組:第一組 NOSA 組(無骨質疏鬆和無肌少症)、第二組 OP 組(僅有骨質疏鬆症)、第三組 OSA 組(骨質疏鬆合併肌少症)及 第四組 SA 組(僅有肌少症)。在收案時進行迷你營養評估(Mini Nutrition Assessment, MNA)、生化檢查、骨密度檢測、身體組成分析及 體位測量。體位測量包含身高、體重、體組成分析。生化檢查包含血中 鈣、磷、維生素 D、白蛋白、球蛋白、總蛋白質等項目，統計分析使用 SPSS version 26.0 版本進行分析。
共招募 70 位受試者，完成試驗者 53 位:NOSA 組(無骨質疏鬆和 無肌少症):11 人;OP 組(僅有骨質疏鬆症):21 人;OSA 組(骨質 疏鬆合併肌少症):21 人;SA 組(僅有肌少症):3 人。多變項邏輯 式回歸分析結果顯示，身體質量指數(body mass index, BMI)和 MNA 與骨鬆肌少症風險呈現負相關。較高的 BMI 和較好的 MNA 營養狀態顯 著與降低疾病風險有關。
The study investigated the nutritional status of patients with osteoporosis and osteosarcopenia and its correlation with bone density, body composition, and blood levels of calcium and vitamin D.
Subjects aged over 50 at high risk for osteoporosis, sarcopenia, and osteosarcopenia were recruited and divided into four groups: group 1: NOSA (neither osteoporosis nor sarcopenia), group 2: OP (osteoporosis only), group 3: OSA (osteoporosis combined with sarcopenia), group 4: SA (sarcopenia only). Upon enrollment, participants underwent a Mini Nutrition Assessment (MNA), biochemical tests, bone density tests, body composition analysis, and anthropometric measurements. The anthropometric measurements included height, weight, and body composition analysis. Biochemical tests included blood levels of calcium, phosphorus, vitamin D, albumin, globulin, and total protein. Statistical analyses were performed using SPSS version 26.0 (SPSS Inc, Chicago).
A total of 70 subjects were recruited, and 53 completed the study: 11 in the NOSA group, 21 in the OP group, 21 in the OSA group, and 3 in the SA group. Multivariate logistic regression analysis showed that body mass index (BMI) and MNA were negatively correlated with the risk of osteosarcopenia. Higher BMI and better nutritional status as indicated by the MNA were significantly associated with a reduced risk of the disease. |
