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    請使用永久網址來引用或連結此文件: http://libir.tmu.edu.tw/handle/987654321/61413


    題名: 以聚氨酯丙烯酸酯基三維列印做為全口假牙基底樹脂之機械性質與生物相容性研究
    Mechanical Properties and Biocompatibility of Urethane Acrylate-Based 3D-Printed Denture Base Resin
    作者: 曾知雋
    TZENG, JY-JIUNN
    貢獻者: 新藥研發產業博士學位學程
    張宏名
    關鍵詞: 聚氨酯;丙烯酸酯;三維列印;全口假牙
    Urethane;Acrylate;3D-printing;Denture
    日期: 2021-07-19
    上傳時間: 2022-03-04 22:31:45 (UTC+8)
    摘要: 將流程自動化是製造業的趨勢，牙體技術產業隨著三維列印機的發展與進步，正試圖將流程繁複的全口假牙製程簡化。本研究以歐特克股份有限公司（Autodesk, Inc., San Rafael, USA）公開的光敏樹脂原料配方為譜，並以較易取得的樹脂單體取代其成分，製作出可供三維列印機使用的光敏樹脂原料，再以三維列印加工並進行材料性質檢測。過去的研究中顯示，透過添加聚氨酯丙烯酸酯能使高分子聚合物展現出較高的柔韌性質。本研究開發出五款添加不同聚氨酯丙烯酸酯的光聚合式三維列印材料，並與市售之光聚合三維列印全口假牙材料進行比較，發現其適合於光聚合三維列印機進行加工，且聚合後之材料具有生物相容性，並擁有較市售產品更佳的機械性質。透過操縱後處理程序，能使聚合後之材料表現出不同顏色，期能符合不同的全口假牙美觀需求。在本研究中所選用之原料配方，其成份易於取得、具經濟效益及商品化的機會，可望在未來成為以光聚合三維列印機製作全口假牙時，所能採用的樹脂原料。
    The trend of manufacturing is to automating. With the development of Additive Manufacturing, the process of making dentures nowadays could be simplified by three-dimensional printing (3D Printing) technics.
    Past studies shown that the adding of urethane-based acrylates could improve the material properties of acrylate polymers. In this study we adapt the photo-curable resin formulation released by “Autodesk, Inc.” and modified the monomers to those which are more easily to obtain. Five different resin materials were formulated by adding different urethane-based acrylates. Material properties, cytotoxicity and the color performance were tested with specimen produced with 3D printers.
    Finally, the resin formulation developed in this study shown better material properties than commercial products. The composition of resins are easily to obtain and has the chance to become a commodity in the future.
    描述: 博士
    指導教授：張宏名
    委員：麥富德
    委員：彭珮雯
    委員：林元敏
    委員：陳儷友
    資料類型: thesis
    顯示於類別:[生技醫療產業研發博士學位學程] 博碩士論文

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