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    請使用永久網址來引用或連結此文件: http://libir.tmu.edu.tw/handle/987654321/60812


    題名: 思覺失調症病患發生失智症的風險:台灣族群的回溯性追蹤研究
    The risk of dementia in patients with schizophrenia: A Taiwanese population retrospective cohort study
    作者: 林敬恩
    Lin, Ching-En
    關鍵詞: 思覺失調症;失智症
    schizophrenia;dementia
    日期: 2016
    上傳時間: 2021-08-13 15:03:07 (UTC+8)
    摘要: 思覺失調症是一個嚴重的精神疾病，在全球的盛行率約1-17‰，
    而在台灣的盛行率則約6.4‰ 。思覺失調症會造成認知功能退化甚至失智症，特別是對於已接近或步入老年的患者更易造成認知衰退，其特徵比失智症更慢性、病程更久。過去國外研究發現思覺失調症可能是罹患失智症的風險因子，然而在台灣卻少有相關研究；本研究利用全民健保資料庫2005年百樣抽樣歸人檔為資料來源進行回溯性追蹤研究，發現有思覺失調症的病患相較於沒有思覺失調症的病患在經過潛在干擾因子校正過後，有顯著較高的失智症罹患風險，推論思覺失調症可能為罹患失智症風險因子。而年齡越大、共病越多者，失智症的發生率亦越高，在人口老化日益增加的台灣，失智症個案數想必也會越發增加；相對的，長照資源耗用於失智症的照護也會日益增加，故早期發現、早期治療思覺失調症，是否能避免病情惡化導致失智症的發生，對於長照資源花費於的節省有否幫助是未來研究的方向。
    Schizophrenia, a serious psychiatric disorder, its prevalence rate was about 1-17 ‰ around the world and about 6.4 ‰ in Taiwan. It would result in cognition deterioration and even dementia, especially in the elderly. It was also characterized with a more chronic course than dementia itself. Several foreign studies have shown schizophrenia itself may be a risk factor of dementia. However, related Taiwanese studies were rare. Our study used 2005 National Health Insurance Data (NHID) as the resource and conducted a retrospective cohort study. We found schizophrenia may be a risk factor of dementia throughout a series of potential confounding factors adjustment. The incidence of dementia was higher in the elderly and those with more comorbid illnesses. The number of dementia will increase in aging Taiwan in the future. On the other hand, the resource of long-term care applied to the care of dementia will also increase. Therefore, whether it is helpful that early detection and treatment of schizophrenia to prevent cognition deterioration and even dementia and to save the cost of long term care, is a direction of the future study.
    描述: 碩士
    指導教授；紀玫如
    資料類型: thesis
    顯示於類別:[長期照護碩士學位學程] 博碩士論文

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