| 摘要: | 過重與肥胖為全世界的公共衛生議題，其存在與代謝性疾病有密切的關係，肥胖
症所衍生出的肥胖間接成本，已經大於直接成本中的醫療保健費用、生產率的降低、
早期死亡率等，因此減重成為降低龐大醫療負擔的一條捷徑。然而，減肥並非單純的
少吃多動，需透過個人化的飲食習慣的建立、代餐營養的調配、生活作息的調整、減
重藥物的輔助、體能活動的增進、心緒壓力的管理等，全方位的監控之下，才能達成
有效率的減重。本次研究，收集2 組不同班別，各別為代餐藥物二合一組及藥物組的
減重病患資料共50 名，自費減重療程為期8 週，在第0、8 週時，進行體組成分析、
腹部超音波檢測，抽8小時空腹血進行生化檢驗分析。之後每一週皆進行體組成追蹤，
使用生物電阻測量儀器分析。2 組減重療程後的體重、腹部脂肪、血脂、血糖及丙酮
酸轉胺酶都有減少，其中代餐藥物二合一組的病患，體重、身體質量指數BMI (Body
Mass Index)、體脂重、空腹血糖皆顯著下降優於藥物組。
Overweight and obesity are public health issues around the world, and their existence is
closely related to metabolic diseases. The indirect cost of obesity derived from obesity,
including direct medical care costs, reduced productivity, and early mortality, has been
greater than direct cost, so weight reduction has become a shortcut to reduce the huge
medical burden. However, weight loss requires the establishment of personalized eating
habits, the deployment of meal replacement nutrition and the assistance of weight loss
drugs, and all-round monitoring to achieve efficient weight loss. In this study, a total of 50 weight loss patients were collected from 2 groups, namely the meal replacement drug
group and the drug group. The weight loss treatment at own expense lasts for 8 weeks. At
the 0th and 8th weeks, body composition analysis, abdominal ultrasound examination, and
blood biochemical analysis were performed. Every week after that, a bioelectrical
impedance (BIA) instrument was used to track body composition. After 8 weeks of the
experiment, the weight, BMI, body fat, and fasting blood glucose of patients in the meal
replacement drug group were significantly lower than those in the drug group. |
