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    題名: 精神分裂病患共病B及C型肝炎之盛行率及醫療利用率
    Prevalence and Health Utilization of Hepatitis B and C Patients With and Without Schizophrenia: A Nationwide Population-Based Study
    作者: 王耀賢
    Wang, Yao-Hsien
    貢獻者: 湯澡薰
    關鍵詞: 醫療利用;精神分裂;B及C型肝炎
    Health Utilization;Hepatitis B and C;Schizophrenia
    日期: 2015-06-05
    上傳時間: 2020-08-19 14:20:12 (UTC+8)
    摘要: Title: Prevalence and Health Utilization of Hepatitis B and C Patients with and without Schizophrenia: A Nationwide Population-Based Study
    Background:
    Taiwan is a hyper endemic country with viral liver diseases. The prevalence of chronic Hepatitis B (HBV) carriers within the general population is approximately 15–20% while Hepatitis C (HCV) infection in the general population is 3–4%. There are very limited studies examining HBV/HCV among patients with schizophrenia.
    Objective:
    To explore the prevalence and health utilization of HBV and HCV patients either with or without schizophrenia
    Method:
    Material under study is a 5-year population-based dataset of Taiwan National Health Insurance claims data files during 2007-2011 on patients with schizophrenia (N= 155,783) and the 1:3 matched comparison group (N= 467,349). HBV/HCV patients are defined as those who had primary ICD-9-CM code = 070.32 for HBV and ICD-9-CM code = 070.54 for HCV. Patients with schizophrenia are defined as those who had primary ICD-9-CM= 295 code in any given year, or those who registered as schizophrenia in the catastrophic registry. Relative risk (RR) of schizophrenia vs. general population group on prevalence and any use of medication intervention was estimated based on a generalized linear model, controlling for age and gender.
    Result:
    The RRs (95% confidence interval [CI]) of patients with schizophrenia comorbid with either HBV or HCV in comparison to general population are 1.5 (1.4-1.5 p<.0001) and 2.1 (2.0-2.2 p<.0001) respectively. Moreover, the RR for patients with schizophrenia comorbid with HBV receiving oral antiviral medication is 0.67 (0.60-0.75 p<.0001) and HCV receiving interferon is 0.41 (0.36-0.48 p<.0001) in comparison to general population.
    Conclusion:
    In Taiwan, patients with schizophrenia have a much higher risk of comorbidity with HBV or HCV than general population. Furthermore, intervention with medication is much less utilized in patients with schizophrenia in comparison to general population. Awareness of comorbidity with viral hepatitis in this special group should be enhanced and interventional treatment should be evaluated thoroughly.
    描述: 碩士
    指導教授:湯澡薰
    委員:蔡世仁
    委員:簡麗年
    資料類型: thesis
    顯示於類別:[醫務管理學系暨研究所] 博碩士論文

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