| 摘要: | 肥胖引起許多健康問題，如代謝性症候群、睡眠呼吸中止症候
群、憂鬱症、心血管疾病、退化性關節炎、下背痛及痛風等。世界各國衛生單位皆將肥胖治療與預防列入相當重要的公共衛生政策。肥胖治療中飲食控制及規律運動是最有效的方法之一。此研究目的探討以相同低熱量，但相異營養素比例進行介入8 週，觀察減重速率及血液生化組成改變，並觀察實驗組8 週後續復胖率。本研究篩選60 位BMI 大於24kg/㎡之體重過重成年人，排除正使用藥物例如：雌激素治療、降血壓、血脂、血糖藥物或罹患肝臟、心臟、腎臟等疾病者等。將受試者隨機分為實驗組及控制組，在1200~1500 大卡熱量飲食控制之下，實驗組為高蛋白質飲食，三大營養素分配為碳水化合物40%，蛋白質30%，脂肪30%，控制組為標準蛋白質飲食，三大營養素分配則為55%，蛋白質15%，脂肪30%。在實驗期第0、8、16 週，測量體位、血液生化值。結果發現，二組在實驗後之體重、身體質量指數、腰圍、收縮壓較第0 週有下降趨勢，三酸甘油酯濃度較第0 週有下降趨勢 (p<0.05) 。而實驗組在第16 週發現腰圍與第0 週相比，具顯著差異(p<0.05)，而與第8 週相比，則無顯著差異。因此，限制熱量之下不論營養素比例進行短期減重，皆具有顯著成效。高蛋白質飲食減重後8 週體重並無顯著回升。
Obesity is associated with several chronic diseases such as metabolic syndromes, obstructive sleep apnea, depression, cardiovascular diseases, degenerative arthritis, low back pain, and gout. It is recognized as very important public policy in the majority of countries all over the world and
warrants many studies. With respect to obesity treatment, dietary control and regular exercise are the cornerstones of therapies. However, the results are rather slow and difficult to be maintained by means of conventional therapies.
This study aimed to compare the effects of an 8-week high protein diet with a conventional low-caloric diet on weight loss, changes of body composition, and rebound of body weight after intervention and follow-up. Sixty obese
adults with body mass index (BMI) greater than 24 kg/m2 were recruited.
Those who were taking estrogen therapy, receiving hyperlipidemia, hypertension and hyperglycemia medication and having liver, renal and heart problems were excluded. Subjects were randomly assigned into two groups, experimental group (high protein diet) and control group (conventional lowcaloric diet). All subjects received 1200~1500 kilocalorie per day. The composition of the experimental diet was carbohydrate 40%, protein 30%,
and fat 30%, while that of the control group was carbohydrate 55%, protein 15%, and fat 30%. The body composition and blood biochemical measurements were analyzed regularly at beginning, 8, and 16 weeks. Results
showed, the average body weights, BMIs, waist circumstances, blood TG, and SP declined in both groups (p < 0.05) at the end of the experiment. At week
16, the waist circumstance was significantly smaller than that at week 0, while insignificantly different from that at week 8. In conclusion, under calorie restriction, weight reduction can be achieved without concerning the diet
composition while consuming high protein diet is a way to maintain the effects. |
