嚴重的膽結石病患中心血管疾病的罹病風險：以族群為基礎的世代研究

English | 正體中文 | 简体中文 | 全文笔数/总笔数 : 45073/58249 (77%)
造访人次 : 2392104 在线人数 : 168

RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.

Taipei Medical University Institutional Repository > 公共衛生暨營養學院 > 公共衛生學系暨研究所 > 碩博論文 > Item 987654321/50371

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://libir.tmu.edu.tw/handle/987654321/50371

题名:	嚴重的膽結石病患中心血管疾病的罹病風險：以族群為基礎的世代研究 Risk of Cardiovascular Disease among Patients with Gallstone Disease: a Population-based Cohort Study
作者:	謬頓, 歐拉亞 Tunbosun, Olaiya Muideen
贡献者:	謝芳宜
关键词:	膽結石,心血管疾病,世代研究,流行病學 Gallstone disease,cardiovascular disease,cohort,epidemiology
日期:	2013-07-10
上传时间:	2018-09-27 15:27:23 (UTC+8)
摘要:	Objective: To investigate whether gallstone disease (GD) increases the risk of developing cardiovascular disease (CVD) in a large population-based cohort. Methods: A study population including 6,981 patients with GD was identified from the Taiwan National Health Insurance Research Database between 2004 and 2005. GD patients were defined as patients with principal discharge diagnoses of cholelithiasis using the International Classification of Diseases, Ninth Revision, Clinical Modication (ICD-9-CM) code 574. 27,924 patients without GD were randomly selected and matched for age and gender. All patients were followed for 6 years or until diagnosis for CVD. Cox proportional hazards regression model was used to assess the risk of developing CVD with adjustment for age, gender and co-morbid conditions. Results: During the six years follow-up period, 940 patients with GD and 2,780 patients without GD developed CVD. Patients with GD had an elevated risk of CVD (HR, 1.32; 95% CI, 1.22-1.42) when compared with those without GD. Similar relationship was observed when CVD was categorized i.e. stroke (HR, 1.23; 95% CI, 1.09-1.39), coronary heart disease (HR, 1.46; 95% CI, 1.33-1.61) and heart failure (HR, 1.54; 95% CI, 1.23-1.91). When GD was classified according to the level of severity, using patients without GD as reference, the risks of CVD were elevated in patients with non-severe GD (HR, 1.36; 95% CI, 1.25-1.49) as well as those with severe GD (HR, 1.20, 95% CI, 1.06-1.36), after adjusting for age, gender and co-morbidities. In age-stratified analysis, patients aged 18-40 years with GD were at higher risk of developing CVD (HR, 1.41; 95% CI, 1.09-1.83) than older GD patients. Conclusion: This study found an increased risk of CVD in patients diagnosed with GD. The excess risk was particularly high in younger GD patients. Prevention of GD could help reduce the risk of developing CVD, and the better effect could be achieved for the younger age groups.
描述:	碩士指導教授-謝芳宜委員-邱弘毅委員-邱月暇
数据类型:	thesis
显示于类别:	[公共衛生學系暨研究所] 碩博論文

文件中的档案:

档案	描述	大小	格式	浏览次数
index.html		0Kb	HTML	434	检视/开启

检视Licence

在TMUIR中所有的数据项都受到原著作权保护.

TAIR相关文章

著作權聲明 Copyright Notice

本平台之數位內容為臺北醫學大學所收錄之機構典藏，包含體系內各式學術著作及學術產出。秉持開放取用的精神，提供使用者進行資料檢索、下載與取用，惟仍請適度、合理地於合法範圍內使用本平台之內容，以尊重著作權人之權益。商業上之利用，請先取得著作權人之授權。
The digital content on this platform is part of the Taipei Medical University Institutional Repository, featuring various academic works and outputs from the institution. It offers free access to academic research and public education for non-commercial use. Please use the content appropriately and within legal boundaries to respect copyright owners' rights. For commercial use, please obtain prior authorization from the copyright owner.
瀏覽或使用本平台，視同使用者已完全接受並瞭解聲明中所有規範、中華民國相關法規、一切國際網路規定及使用慣例，並不得為任何不法目的使用TMUIR。
By utilising the platform, users are deemed to have fully accepted and understood all the regulations set out in the statement, relevant laws of the Republic of China, all international internet regulations, and usage conventions. Furthermore, users must not use TMUIR for any illegal purposes.
本平台盡力防止侵害著作權人之權益。若發現本平台之數位內容有侵害著作權人權益情事者，煩請權利人通知本平台維護人員([email protected])，將立即採取移除該數位著作等補救措施。
TMUIR is made to protect the interests of copyright owners. If you believe that any material on the website infringes copyright, please contact our staff([email protected]). We will remove the work from the repository.

数据加载中.....