鈦基合金表面生成二氧化鈦薄膜之生物相容性研究

English | 正體中文 | 简体中文 | 全文筆數/總筆數 : 45422/58598 (78%)
造訪人次 : 2534816 線上人數 : 241

RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.

Taipei Medical University Institutional Repository > 口腔醫學院 > 牙醫學系 > 博碩士論文 > Item 987654321/44557

請使用永久網址來引用或連結此文件: http://libir.tmu.edu.tw/handle/987654321/44557

題名:	鈦基合金表面生成二氧化鈦薄膜之生物相容性研究 Research of biocompatibility on titanium-based alloy with titanium dioxide film
作者:	陳宜妤 Yi-Yu Chen
貢獻者:	牙醫學系碩博士班
關鍵詞:	鈦金屬;表面處理;牙科植體;titanium;surface treatment;dental implant
日期:	2011
上傳時間:	2011-11-03 16:55:41 (UTC+8)
摘要:	牙科植體漸漸成為治療缺牙區的選項之一時，許多學者便致力於研究植體與組織的交互作用，經由表面形態的改變，追求更有效率的骨整合。已有研究提出鈦金屬表面形成的氧化層跟其優良的生物相容性有關，因此瞭解氧化層的性質與改變氧化層的結構、形態、厚度等，讓人甚感興趣。本實驗利用電漿處理的表面處理方式，得到不同表面氧化層的鈦金屬試片，以人類骨肉瘤細胞培養後觀察其所呈現的細胞形態以及與試片接觸的情形，同時比較血液相容性的差異。結果顯示經過處理的鈦金屬，其生物相容性與血液相容性都有改善的現象。 The biocompatibility of titanium is closely related with the surface oxide film. The improvement of the biological activity of titanium with plasma immersion on implantation has been investigated. However, the effects of oxygen ion implantation on the titanium were still lack. In this study, the titanium plates were implanted with oxygen at different power conditions and subsequently analyzed for surface morphologies and phase composition. To observe the effect of oxygen ion implantation on cell behavior, MG-63 osteoblast-like cells were cultured on the treated titanium plates. The hemocompatibility was determined by measuring the adhesion of blood platelets and fibrinogen, P-selectine expression, and the blood clotting time on these modified titanium plates. The results revealed that MG-63 osteoblast-like cells expressed better response on the surface-treated titanium plates. Furthermore, the results of clotting time assay demonstrated titanium treated by oxygen ion power could promote blood coagulation. The titanium plates treated with 1 KW ion power revealed better expression of platelets and fibrinogen adhesion, which showed the higher average roughness. In conclusion, the biocompatibility and hemocompatibility of titanium-based alloy can potentially be improved by plasma immersion oxygen ion implantation.
顯示於類別:	[牙醫學系] 博碩士論文

文件中的檔案:

檔案	大小	格式	瀏覽次數
鈦基合金表面生成二氧化鈦薄膜之生物相容性研究.pdf	4059Kb	Adobe PDF	103	檢視/開啟

在TMUIR中所有的資料項目都受到原著作權保護.

TAIR相關文章

著作權聲明 Copyright Notice

本平台之數位內容為臺北醫學大學所收錄之機構典藏，包含體系內各式學術著作及學術產出。秉持開放取用的精神，提供使用者進行資料檢索、下載與取用，惟仍請適度、合理地於合法範圍內使用本平台之內容，以尊重著作權人之權益。商業上之利用，請先取得著作權人之授權。
The digital content on this platform is part of the Taipei Medical University Institutional Repository, featuring various academic works and outputs from the institution. It offers free access to academic research and public education for non-commercial use. Please use the content appropriately and within legal boundaries to respect copyright owners' rights. For commercial use, please obtain prior authorization from the copyright owner.
瀏覽或使用本平台，視同使用者已完全接受並瞭解聲明中所有規範、中華民國相關法規、一切國際網路規定及使用慣例，並不得為任何不法目的使用TMUIR。
By utilising the platform, users are deemed to have fully accepted and understood all the regulations set out in the statement, relevant laws of the Republic of China, all international internet regulations, and usage conventions. Furthermore, users must not use TMUIR for any illegal purposes.
本平台盡力防止侵害著作權人之權益。若發現本平台之數位內容有侵害著作權人權益情事者，煩請權利人通知本平台維護人員([email protected])，將立即採取移除該數位著作等補救措施。
TMUIR is made to protect the interests of copyright owners. If you believe that any material on the website infringes copyright, please contact our staff([email protected]). We will remove the work from the repository.

資料載入中.....