Gene Variants of Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) and Risks of  Ischemic Stroke in the Taiwanese Population.

English | 正體中文 | 简体中文 | 全文筆數/總筆數 : 45422/58598 (78%)
造訪人次 : 2517477 線上人數 : 216

RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.

Taipei Medical University Institutional Repository > 醫學科技學院 > 醫學檢驗暨生物技術學系所 > 期刊論文 > Item 987654321/3753

請使用永久網址來引用或連結此文件: http://libir.tmu.edu.tw/handle/987654321/3753

題名:	Gene Variants of Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) and Risks of Ischemic Stroke in the Taiwanese Population.
作者:	謝銘松;李宏謨 Ming-Song Hsieh;Shu-Chuan Yu;Yu-Mei Hsueh;Wen Ta-Chiu;Horng-Mo Lee
貢獻者:	醫學檢驗暨生物技術學系
關鍵詞:	genetics;stroke;single-nucleotide polymorphism (SNP);ALOX5AP
日期:	2008
上傳時間:	2009-08-25 10:38:19 (UTC+8)
摘要:	It has been shown that stroke in the Icelandic population may be attributed to gene variations in 5-lipoxygenaseactivating protein (ALOX5AP) gene. Because the linkage between the gene variations of these genes and ischemic stroke in Taiwan has not been reported, we evaluated whether ALOX5AP gene polymorphisms confers risk of ischemic stoke in Taiwanese patients. Four singlenucleotide polymorphisms (SNPs) covering the ALOX5AP gene were genotyped using genomic DNA sequencing and a high-throughput TaqMan PCR assay in 108 patients suffering ischemic stroke and 280 healthy individuals. No significant associations with ischemic stroke were observed with SNPs HapA (SG13S32 and SG13S89) and HapB (SG13S41 and SG13S35) from ALOX5AP, which were a part of the Icelandic at-risk haplotypes. The present data do not support a significant role for ALOX5AP polymorphisms in a genetic susceptibility to ischemic stroke in the Taiwanese population.
關聯:	Clinical Molecular Medicine.(1):1-5.
資料類型:	article
顯示於類別:	[醫學檢驗暨生物技術學系所] 期刊論文

文件中的檔案:

檔案	描述	大小	格式	瀏覽次數
全文.txt		0Kb	Text	137	檢視/開啟
摘要.pdf		35Kb	Adobe PDF	145	檢視/開啟

在TMUIR中所有的資料項目都受到原著作權保護.

TAIR相關文章

著作權聲明 Copyright Notice

本平台之數位內容為臺北醫學大學所收錄之機構典藏，包含體系內各式學術著作及學術產出。秉持開放取用的精神，提供使用者進行資料檢索、下載與取用，惟仍請適度、合理地於合法範圍內使用本平台之內容，以尊重著作權人之權益。商業上之利用，請先取得著作權人之授權。
The digital content on this platform is part of the Taipei Medical University Institutional Repository, featuring various academic works and outputs from the institution. It offers free access to academic research and public education for non-commercial use. Please use the content appropriately and within legal boundaries to respect copyright owners' rights. For commercial use, please obtain prior authorization from the copyright owner.
瀏覽或使用本平台，視同使用者已完全接受並瞭解聲明中所有規範、中華民國相關法規、一切國際網路規定及使用慣例，並不得為任何不法目的使用TMUIR。
By utilising the platform, users are deemed to have fully accepted and understood all the regulations set out in the statement, relevant laws of the Republic of China, all international internet regulations, and usage conventions. Furthermore, users must not use TMUIR for any illegal purposes.
本平台盡力防止侵害著作權人之權益。若發現本平台之數位內容有侵害著作權人權益情事者，煩請權利人通知本平台維護人員([email protected])，將立即採取移除該數位著作等補救措施。
TMUIR is made to protect the interests of copyright owners. If you believe that any material on the website infringes copyright, please contact our staff([email protected]). We will remove the work from the repository.

資料載入中.....