 |
English
|
正體中文
|
简体中文
|
全文笔数/总笔数 : 45073/58249 (77%)
造访人次 : 2390849
在线人数 : 167
|
|
|
数据加载中.....
|
jsp.display-item.identifier=請使用永久網址來引用或連結此文件:
http://libir.tmu.edu.tw/handle/987654321/37080
|
| 题名: | Tissue plasminogen activator therapy of renal venous thrombosis |
| 作者: | Wang KY, Tsai LW, *Chen CM. |
| 贡献者: | Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan |
| 关键词: | Renal venous thrombosis, recombinant tissue plasminogen activator |
| 日期: | 2008 |
| 上传时间: | 2010-11-16 09:57:47 (UTC+8) |
| 摘要: | Background: Neonatal renal venous thrombosis (RVT) is a well documented and potentially fatal entity with long-term renal morbidity.
Case Report: We report an unusual case of bilateral RVT in a premature infant with persistent pulmonary hypertension and the use of recombinant tissue plasminogen activator (r-TPA) was associated with a successful outcome and final complete recovery. A 2850 gm, 36-week preterm male baby was born to a 29-year-old woman via emergency cesarean section due to preeclampsia and fetal heart rate deceleration. The infant required high frequency mechanical ventilation for poor respiratory effort and low oxygenation, insertion of umbilical catheters for resuscitation, cardiac massages for stabilizing blood pressure, and claforan and ampicillin for presumed sepsis. Laboratory studies revealed hemoglobin, 12.3 g/dl; hematocrit, 39.3%; platelet, 53,000/mm3; blood urea nitrogen, 26 mg/dL; creatinine, 2.8 mg/dL; and metabolic acidosis on day 3. Bilateral abdominal palpable mass and gross hematuria with blood clot was found on day 3 and the renal ultrasound showed swollen kidneys with prominent echopoor medullary pyramids. Given the extensive nature of the thrombus and the presence of progressively deteriorated renal function, systemic thrombolytic therapy using r-TPA at a dose of 0.1 mg/kg/hr was administered for 8 hours on day 10 after correction of thrombocytopenia on days 3 and 6. Renal functions returned to normal on day 19 and the follow-up ultrasound showed normal renal sizes at 7 months old.
Conclusions: The presence of either a flank mass, hematuria, or thrombocytopenia in a neonate with risk factors should prompt investigation for RVT in order to prevent long-term renal morbidity. |
| 關聯: | Arch Dis Child Fetal Neonatal Ed. 2008;93:F397-F398. |
| 显示于类别: | [小兒學科] 期刊論文
|
文件中的档案:
| 档案 |
大小 | 格式 | 浏览次数 |
|---|
| F397-a.pdf | 116Kb | Adobe PDF | 56 | 检视/开启 |
|
在TMUIR中所有的数据项都受到原著作权保护.
|
