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| 題名: | 飲食中鈣質介入體重控制計畫對於體重過重及肥胖者減重成效之評估
Effect of Daily Calcium Intervention on the Effectiveness of Weight loss in the Overweight or Obese Humans |
| 作者: | 林若君
Lin Jo-Chun |
| 貢獻者: | 保健營養學研究所
簡怡雯 |
| 關鍵詞: | 碩士
指導教授-簡怡雯
委員-黃惠宇
委員-胡雪萍
肥胖;低熱量飲食;體重控制;減重;鈣質;副甲狀腺素
obesity;energy restricted diet;weight loss calcium;parathyroid hormone (PTH) |
| 日期: | 2010 |
| 上傳時間: | 2010-10-20 12:41:58 (UTC+8) |
| 摘要: | 本研究目的主要是探討對於體重過重或肥胖者，給予高鈣低熱量飲食介入體重控制計畫，對於減重成效與體組成之影響，藉以了解在體重控制中提供足夠的鈣質攝取是否能改善體重過重或肥胖者體內脂肪量。本實驗受試者為平日鈣攝取量少於500毫克/天，且健康的體重過重或肥胖者 (BMI：25~30 公斤/(公尺)2) 共42位，隨機且雙盲分成高鈣組 (每日攝取兩份高鈣代餐) 以及控制組，人數各為21人，分別有16位女性及5位男性。兩組提供8週的低熱量飲食 (熱量：1200大卡/天，醣類：55%，脂肪：25%，蛋白質：20%)，並於實驗第0週與第8週進行3日飲食紀錄、體組成以及血液生化值的分析。由飲食分析的結果顯示，在鈣質攝取量的部分，高鈣組實驗後平均鈣質攝取量為964.5 ± 75.5毫克，明顯大於控制組的353.7 ± 96.6毫克 (p<0.05)；減重8週後，兩組在體重、BMI、體脂肪、體脂肪百分比、腰圍、腰臀比、血中總膽固醇、三酸甘油酯、LDL-C濃度、TC/HDL-C的比值均較減重前顯著的下降。此外，高鈣組的體重 (-6.9 ± 3.3 公斤, p<0.05)、BMI (-2.7 ± 1.1公斤/(公尺)2, p<0.01)、體脂肪 (-5.7 ± 2.7 公斤, p<0.05)、體脂肪百分比 (-5.7 ± 2.7 公斤, p<0.05) 以及TC/HDL-C的比值 (-0.4 ± 0.6, p<0.05) 皆比控制組顯著的降低。在血清副甲狀腺素的部分，高鈣組在實驗第8週明顯低於第0週 (p<0.05)，而血清副甲狀腺素的濃度與鈣質的攝取呈現負相關。因此，在限制熱量攝取的減重條件下，給予體重過重或肥胖者足夠的含鈣飲食，可增加體重控制的效益。
The purpose of this study was to assess the impacts of dietary calcium intervention on effectiveness of weight loss program in obese. All subjects had an initial BMI (body fat index) >24 kg/m2 and low calcium diet (<500 mg/d). Forty two healthy overweight or obese were randomly and equally divided into two groups: Hi-Ca group (female: 16, male: 5) and control group (female: 16, male: 5). In Hi-Ca group, we provided two bottles of Hi-Ca drinks per day and low energy diet (energy: 1200 kcal, carbohydrate: 55%, fat: 25%, protein: 20%) for 8 weeks. In control group, we only provided low energy diet for 8 weeks. We measured 3-day-food record, anthropometric and blood biochemical data respectively at week 0 and week 8. After 8 weeks, results showed that the calcium intake was 964.5 ± 75.5 mg in Hi-Ca group is where 353.7 ± 96.6 mg in control group (p<0.05). Besides, the loss of body weight (-6.9 ± 3.3 kg, p<0.05), BMI (-2.7 ± 1.1 kg/m2, p<0.01), body fat mass (-5.7 ± 2.7 kg, p<0.05), body fat percentage (-4.4 ± 1.9 %, p<0.002) and TC/HDL-C (-0.4 ± 0.6, p<0.05) in Hi-Ca group were significantly different from those of control group in 8 weeks. In the of lipid profile, serum cholesterol, triglyceride and LDL-C concentration were significantly decreased compared with those in week 0. In the serum PTH (parathyroid hormone) level, Hi-Ca group was significantly lowered compared with the baseline (-5.3 ± 10.4 pg/mL, p<0.05) in week 0, which showed that the concentration of PTH and calcium intake were negative correlation and indicated that using high calcium diet together with low energy diet on weight loss program had more significant decreasing in body weight, BMI, body fat mass, and body fat percentage. Therefore, under the circumstance of energy restricted diet, it would increase the effectiveness on weight loss that giving high calcium diet to those overweight and obese humans. |
| 關聯: | 108頁 |
| 描述: | 摘 要…………………………………………………………………I
英文摘要………………………………………………………………...II
致 謝………………………………………………………………..III
目 錄………………………………………………………………..IV
表 目 錄……………………………………………………...…..……VII
圖 目 錄……………………………………………………..…….…VIII
附錄目錄…………………………………………………….………….IX
第一章 緒論………………………………………………………..…....1
第一節 研究動機………………………………………………...…1
第二節 研究目的…………………………………………………...3
第二章 文獻回顧…………………………………………………………4
第一節 肥胖定義與盛行率………………………………………...4
第二節 肥胖對健康的危害………………………………………...7
第三節 肥胖的成因……………………………………….………10
第四節 國人鈣質攝取現況……………………………………….12
第五節 鈣質的生理作用………………………….………………14
第六節 飲食中的鈣質型式與影響因子…………….……………16
第七節 鈣質與骨骼的相關性…………………………….………18
第八節 鈣質與肥胖的相關性……………………………….……20
第九節 鈣質調控體重的機制.. ……………………….………….23
第三章 實驗設計與方法……………………………..…………….….27
第一節 研究執行流程圖與實驗設計………………..…...…27
第二節 研究對象……………………………………………….…29
第三節 飲食介入……………………………………………….…30
第四節 研究項目………………………………………………….31
第五節 統計方法………………………………………………….40
第四章 結果…………………………………………………………....41
第一節 受試者基本資料……………………………………….…41
第二節 受試者減重前後營養素的攝取狀況………………....…43
第三節 減重期間體位測量值之變化……………………...…..…45
第四節 減重期間對血脂質濃度的影響……………………..….50
第五節 減重期間對副甲狀腺素濃度的影響…………………...53
第六節 鈣質變化量、甲狀腺素、體位變異數相關性………….…54
第七節 減重期間對肝功能與腎功能指數之影響……………..55
第五章 討論…………………………………………………………56
第一節 高鈣低熱量飲食對受測者減重成效之探討………….…56
第二節 高鈣低熱量飲食對於受測者血液生化值之探討….....61
第三節 血清副甲狀腺素濃度與減重效果的關係…...………..…64
第六章 結論…………………………………………………..………..67
第七章 參考文獻………………………………………………………85
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