| 描述: | 目錄
標題 I
審定書 II
誌謝 III
目錄 IV
表目錄 VII
圖目錄 VIII
論文摘要 X
ABSTRACT XIII
第一章、 緒論 1
1.1 研究背景 1
1.2 研究動機 2
1.3 研究目的 4
第二章、 文獻探討 5
2.1 用藥疏失(MEDICATION ERROR) 5
2.1.1 藥物不良事件ADEs 6
2.1.2 可預期的藥物不良反應 7
2.1.3 不可預期的不良反應 7
2.1.4 藥物不良反應通報系統 7
2.2 臨床決策支援系統探討及評估 8
2.2.1 可行性 9
2.2.2 臨床監測系統相關之文獻探討 9
2.2.3 檢驗端監控之相關文獻 12
2.3 藥物探討之抗凝血藥物(WARFARIN) 15
2.3.1 Warfarin之作用機轉 15
2.3.2 Warfarin之監測參數 16
2.3.3 起始劑量 16
2.3.4 維持劑量 16
2.3.5 INR 17
2.3.6 抗凝血決策支援系統相關之文獻探討 17
2.4 藥物探討之CARBAMAZEPINE 18
2.4.1 作用機制 19
2.4.2 監測參數 19
2.4.3 副作用 19
2.5 藥物探討之METFORMIN 20
2.5.1 作用機制 20
2.5.2 監測參數 20
2.5.3 副作用 21
2.6 整理藥物與所需檢驗資料 22
第三章、 研究材料與方法 23
3.1 研究架構 23
3.2 KNOWLEDGE BASE建置規則 24
3.3 系統軟硬體需求 24
3.3.1 建構於藥師端智慧型用藥安全警示系統之需求 25
3.3.2 住院端藥師用藥安全警示系統查詢介面 26
3.3.3 建構系統開發環境 26
3.4 方法 27
3.4.1 使用操作流程圖 27
3.4.2 Warfarin之作業流程圖 29
3.4.3 Carbamazepine之作業流程圖 30
3.4.4 Metformin之作業流程圖 31
3.4.5 系統整體架構 32
3.5 系統評估 33
第四章、 研究成果 34
4.1 系統查詢功能 34
4.1.1 住院病患查詢 34
4.1.2 高風險用藥清單查詢 38
4.1.3 藥物資訊查詢功能 50
4.2 系統評估分析 59
第五章、 討論與結論 66
5.1 討論 66
5.2 結論 68
5.2.1 研究限制 69
5.2.2 未來展望 69
參考文獻 71
參考文獻
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