English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 45279/58455 (77%)
造訪人次 : 2489565      線上人數 : 167
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋


    請使用永久網址來引用或連結此文件: http://libir.tmu.edu.tw/handle/987654321/3237


    題名: Detecting Mycobacterium Tuberculosis in BACTEC MGIT 960 Cultures by COBAS AMPLICOR MTB in Routine Clinical Practice
    作者: 白冠壬;李俊年;余明治
    Bai KJ;Yu FL;Jou R;Wang MS;Lin MH;Lee CN;Yu MC
    貢獻者: 呼吸治療學系
    日期: 2008
    上傳時間: 2009-08-24 11:31:56 (UTC+8)
    摘要: 快速、自動的結核菌培養偵測系統BACTEC MGIT 960已在台灣廣為應用；然而，目前非結核性分枝桿菌在臨床實驗室的高分離率也造成診斷上的困擾。此研究主要目的為評估COBAS AMPLICOR MTB在BACTEC MGIT 960陽性檢體的臨床應用。研究方法：從2006年3月1日到2007年2月28日共有270個BACTEC MGIT 960陽性檢体在台北醫學大學•萬芳醫院進行COBAS AMPLICOR MTB檢驗，並與傳統生化菌株鑑定的結果進行比較。結果：207(76.7%)個COBAS AMPLICOR MTB檢驗有決定性結論，63（3株為結核菌，60株為非結核性分枝桿菌）個檢驗無決定性結論。在176個結果為陽性者，174個檢驗為真陽性，2個檢驗為偽陽性。在31個結果為陰性者，30個檢驗為真陰性，1個檢驗為偽陰性。若不考慮檢驗結果為無決定性結論者，此項應用的敏感性、特異性、陽性預測值與陰性預測值分別為99%、94%、99%及97%。結論：COBAS AMPLICOR MTB可能適合作為BACTEC MGIT 960陽性檢體快速偵測及鑑定結核菌的檢驗工具。
    Introduction: The rapid, automated cultivation and detection system, BACTEC MGIT 960, is widely used in Taiwan. But the high nontuberculous mycobacteria (NTM) isolation rate is a concern that should be carefully evaluated. The aim of this study was to evaluate the ability of the commercial COBAS AMPLICOR MTB amplification system to identify Mycobacterium tuberculosis (M. tuberculosis) in positive BACTEC MGIT 960 cultures in routine clinical practice. Methods: We tested 270 positive BACTEC MGIT 960 cultures with the COBAS AMPLICOR MTB at Taipei Medical University-Wan Fang Hospital from March 1, 2006 through February 28, 2007. The COBAS AMPLICOR MTB results were compared with mycobacterial species identification by conventional biochemical testing. Results: We found that 207 (76.7%) COBAS AMPLICOR MTB results were regarded as conclusive, and 63 (3 M. tuberculosis, 60 NTM) inconclusive. Among 176 conclusive results positive for M. tuberculosis, 174 were regarded as true positive and 2 false positive. Among 31 conclusive results negative for M. tuberculosis, 30 were regarded as true negative and 1 false negative. After excluding the inconclusive results, we further found that the sensitivity, specificity, and positive/negative predictive values of the COBAS AMPLICOR MTB test were 99, 94, 99, and 97%, respectively. Conclusion: COBAS AMPLICOR MTB might be suitable for rapid detection and identification of M. tuberculosis in BACTEC MGIT 960 cultures in routine clinical practice.
    關聯: Thorac Med.(23):156-63.
    資料類型: article
    顯示於類別:[呼吸治療學系] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    WFC-10.pdf685KbAdobe PDF416檢視/開啟
    全文.txt0KbText210檢視/開啟
    摘要.pdf53KbAdobe PDF317檢視/開啟


    在TMUIR中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    著作權聲明 Copyright Notice

    • 本平台之數位內容為臺北醫學大學所收錄之機構典藏，包含體系內各式學術著作及學術產出。秉持開放取用的精神，提供使用者進行資料檢索、下載與取用，惟仍請適度、合理地於合法範圍內使用本平台之內容，以尊重著作權人之權益。商業上之利用，請先取得著作權人之授權。

      The digital content on this platform is part of the Taipei Medical University Institutional Repository, featuring various academic works and outputs from the institution. It offers free access to academic research and public education for non-commercial use. Please use the content appropriately and within legal boundaries to respect copyright owners' rights. For commercial use, please obtain prior authorization from the copyright owner.

    • 瀏覽或使用本平台，視同使用者已完全接受並瞭解聲明中所有規範、中華民國相關法規、一切國際網路規定及使用慣例，並不得為任何不法目的使用TMUIR。

      By utilising the platform, users are deemed to have fully accepted and understood all the regulations set out in the statement, relevant laws of the Republic of China, all international internet regulations, and usage conventions. Furthermore, users must not use TMUIR for any illegal purposes.

    • 本平台盡力防止侵害著作權人之權益。若發現本平台之數位內容有侵害著作權人權益情事者，煩請權利人通知本平台維護人員([email protected])，將立即採取移除該數位著作等補救措施。

      TMUIR is made to protect the interests of copyright owners. If you believe that any material on the website infringes copyright, please contact our staff([email protected]). We will remove the work from the repository.

    Back to Top
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋