Effects of dietary intake on glucose metabolism and reproductive hormones in women with polycystic ovary syndrome. Ann. Nutr. Metab

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Title:	Effects of dietary intake on glucose metabolism and reproductive hormones in women with polycystic ovary syndrome. Ann. Nutr. Metab
Authors:	Wang TW;Chao JC;Wei HJ;Young R;Liaw CM;Tsai YH;Lin YL;Wang SS
Contributors:	School of Nutrition and Health Sciences, Taipei Medical University
Keywords:	PCOS;insulin resistance;dietary;fat
Date:	2009-09
Issue Date:	2009-12-15 15:16:18 (UTC+8)
Abstract:	Objective: To understand the relationship of dietary intake on glucose metabolism and reproductive hormones in patients with polycystic ovary syndrome (PCOS) in Taiwan. Design: Cross-sectional study. Setting: Infertility Center, Taiwan Adventist Hospital. Patients: Thirty-one patients with PCOS and thirty-six control infertility patients. Intervention(s): None. Main Outcomes Measure(s): Hormones assay, 75-g oral glucose tolerance test, 24-hour recall and 3-d dietary record. Results: PCOS patients increased BMI and body fat percentage compared with non-PCOS patients. Significant positive correlations were observed between calorie intake and fasting blood glucose (r = 0.47, P < 0.05), fasting insulin (r = 0.37, P < 0.05), insulin resistance (r = 0.41, P < 0.05). Plasma testosterone concentration was positively correlated with dietary carbohydrate intake (r = 0.40, P < 0.01). Postprandial glucose concentration was positively correlated with dietary fat intake (r = 0.45, P < 0.05). Conclusions: PCOS women with greater BMI and body fat impair glucose metabolism and insulin sensitivity. Fat and carbohydrate intake is positively correlated with plasma testosterone and postprandial glucose concentrations, respectively.
Relation:	Ann Nutr Metab. 55 (suppl 1): pp. 194 (P11-04).
Appears in Collections:	[School of Nutrition and Health Sciences] Posters

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