Taipei Medical University Institutional Repository:Item 987654321/13766
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    Please use this identifier to cite or link to this item: http://libir.tmu.edu.tw/handle/987654321/13766


    Title: Efficient Synthses of Redox-Switched Naphthoquinone Thiol-Crown Ethers and Their Biological Activity Evaluation
    Authors: 郭憲壽
    Huang ST;Kuo HS;Hsiao CL;& Lin YL
    Contributors: 醫學系生化學科
    Date: 2002
    Issue Date: 2009-10-28 13:55:13 (UTC+8)
    Abstract: Series of naphthoquinone thiol-crown ethers had been prepared. The antibacterial, antifungal, and cytotoxic activities of these synthetic naphthoquinone thiol-crown ethers were investigated. All of the compounds tested displayed antibacterial, cytotoxic and antifungal activities. The bis-naphthoquinone thiol-crown ether 7a was the most potent inhibitor among tested analogues against Staphylococcus aureus methicillin resistance with MIC value of 2.68 microM.
    Relation: Bioorganic & Chemistry.():1947-1952.
    Data Type: article
    Appears in Collections:[Department of Biochemistry and Molecular Cell Biology] Periodical Article

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    摘要.pdf34KbAdobe PDF128View/Open


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